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CCM2


Official Full Name
CCM2 scaffold protein
Organism
Homo sapiens
Gene ID
83605
Background
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
Synonyms
OSM; C7orf22; PP10187

Cat.No. Product Name Price
SHH257745 shRNA set against Human CCM2 (NM_031443.3) Inquiry
SHH257749 shRNA set against Mouse CCM2 (NM_146014.3) Inquiry
SHW003110 shRNA set against Chicken CCM2 (NM_001197144) Inquiry
SHW006350 shRNA set against Danio rerio CCM2 (NM_001002315) Inquiry
Cat.No. Product Name Price
MiUTR3H-09582 CCM2 miRNA 3'UTR clone Inquiry
CDFR009477 Rat Ccm2 cDNA Clone(NM_001126275.1) Inquiry
CDFH002956 Human CCM2 cDNA Clone(NM_001167935.1) Inquiry
CDFH002955 Human CCM2 cDNA Clone(NM_001167934.1) Inquiry
CDFG005440 Human CCM2 cDNA Clone(NM_031443.3) Inquiry
CDFG005439 Human CCM2 cDNA Clone(NM_031443.3) Inquiry
CDCS418281 Human CCM2 ORF Clone (BC004903) Inquiry
MiUTR3H-09581 CCM2 miRNA 3'UTR clone Inquiry
CDCS418282 Human CCM2 ORF Clone (BC063663) Inquiry
CDCR376538 Rat Ccm2 ORF Clone(NM_001126275.1) Inquiry
CDCR243117 Mouse Ccm2 ORF Clone(NM_001190344.1) Inquiry
CDCR043448 Mouse Ccm2 ORF clone (NM_001190343.1) Inquiry
CDCR043444 Human CCM2 ORF clone (NM_001167934.1) Inquiry
CDCR043442 Human CCM2 ORF clone (NM_001167935.1) Inquiry
CDCB191781 Rabbit CCM2 ORF clone (XM_008261829.1) Inquiry
CDCB167825 Danio rerio CCM2 ORF Clone (NM_001002315) Inquiry
CDCR311186 Human CCM2 ORF Clone(NM_031443.3) Inquiry
CDCB164585 Chicken CCM2 ORF Clone (NM_001197144) Inquiry
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