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ZCCHC8


Official Full Name
zinc finger CCHC-type containing 8
Organism
Homo sapiens
Gene ID
55596
Background
This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017]
Synonyms
PFBMFT5

Cat.No. Product Name Price
SHH449744 shRNA set against Human ZCCHC8 (NM_017612.3) Inquiry
SHH449748 shRNA set against Mouse ZCCHC8 (NM_027494.3) Inquiry
SHH449752 shRNA set against Rat ZCCHC8 (NM_001105929.1) Inquiry
SHW001309 shRNA set against Chicken ZCCHC8 (NM_001030662) Inquiry
SHW011326 shRNA set against Danio rerio ZCCHC8 (NM_001083818) Inquiry
Cat.No. Product Name Price
CDFR005657 Rat Zcchc8 cDNA Clone(NM_001105929.1) Inquiry
MiUTR3H-16648 ZCCHC8 miRNA 3'UTR clone Inquiry
CDCB162784 Chicken ZCCHC8 ORF Clone (NM_001030662) Inquiry
CDCB172801 Danio rerio ZCCHC8 ORF Clone (NM_001083818) Inquiry
CDCB191555 Rabbit ZCCHC8 ORF clone (XM_008250524.1) Inquiry
CDCR259755 Mouse Zcchc8 ORF Clone(NM_027494.3) Inquiry
CDCR372735 Rat Zcchc8 ORF Clone(NM_001105929.1) Inquiry
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