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XRCC5


Official Full Name
X-ray repair cross complementing 5
Organism
Homo sapiens
Gene ID
7520
Background
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Synonyms
KU80; KUB2; Ku86; NFIV; KARP1; KARP-1

Cat.No. Product Name Price
SHH448128 shRNA set against Human XRCC5 (NM_021141.3) Inquiry
SHH448132 shRNA set against Mouse XRCC5 (NM_009533.2) Inquiry
SHH448136 shRNA set against Rat XRCC5 (NM_177419.2) Inquiry
SHL139022 shRNA set against Mouse Xrcc5(NM_009533.2) Inquiry
SHW008203 shRNA set against Danio rerio XRCC5 (NM_001017360) Inquiry
Cat.No. Product Name Price
CDCR247428 Mouse Xrcc5 ORF Clone(NM_009533.2) Inquiry
MiUTR1M-12859 XRCC5 miRNA 3'UTR clone Inquiry
MiUTR3H-02422 XRCC5 miRNA 3'UTR clone Inquiry
CDCB169678 Danio rerio XRCC5 ORF Clone (NM_001017360) Inquiry
CDCB189221 Rabbit XRCC5 ORF clone (XM_002712463.2) Inquiry
CDCL186794 Human XRCC5 ORF clone(NM_021141.3) Inquiry
CDCR381938 Rat Xrcc5 ORF Clone(NM_177419.2) Inquiry
CDCS415294 Human XRCC5 ORF Clone (BC019027) Inquiry
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