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VDR


Official Full Name
vitamin D receptor
Organism
Homo sapiens
Gene ID
7421
Background
This gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though this receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jun 2018]
Synonyms
NR1I1; PPP1R163

Cat.No. Product Name Price
SHH442552 shRNA set against Mouse VDR (NM_009504.4) Inquiry
SHH442556 shRNA set against Rat VDR (NM_017058.1) Inquiry
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SHW005598 shRNA set against Chicken VDR (NM_205098) Inquiry
SHH442548 shRNA set against Human VDR (NM_000376.2) Inquiry
SHL122624 shRNA set against Human VDR(NM_000376.2) Inquiry
Cat.No. Product Name Price
CDCB167073 Chicken VDR ORF Clone (NM_205098) Inquiry
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CDCL186714 Mouse VDR ORF clone(NM_009504.4) Inquiry
CDCR341881 Human VDR ORF Clone(NM_001017535.1) Inquiry
CDCR378158 Rat Vdr ORF Clone(NM_017058.1) Inquiry
CDFH021051 Human VDR cDNA Clone(NM_000376.2) Inquiry
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MiUTR1H-11111 VDR miRNA 3'UTR clone Inquiry
MiUTR1R-08515 VDR miRNA 3'UTR clone Inquiry
CDCB195572 Rabbit VDR ORF clone (XM_008251852.1) Inquiry
CDCH099368 human VDR ORF clone (NM_001017536.1) Inquiry
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