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VMP1

Official Full Name
vacuole membrane protein 1
Organism
Homo sapiens
GeneID
81671
Background
This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy. [provided by RefSeq, Jul 2016]
Synonyms
EPG3; TANGO5; TMEM49;

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