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VIMP


Official Full Name
selenoprotein S
Organism
Homo sapiens
Gene ID
55829
Background
This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR of this mRNA have been shown to function as modulators of Sec insertion. An alternatively spliced transcript variant, lacking the SECIS element and encoding a non-Sec containing shorter isoform, has been described for this gene (PMID:23614019). [provided by RefSeq, Jul 2017]
Synonyms
SELENOS; SELS; VIMP; ADO15; SBBI8; SEPS1; AD-015

Cat.No. Product Name Price
SHH310037 shRNA set against Mouse H47 (NM_024439.3) Inquiry
SHH404160 shRNA set against Human SELS (NM_203472.1) Inquiry
SHH404164 shRNA set against Rat SELS (NM_173120.2) Inquiry
SHR213040 shRNA set against Human SELS(NM_018445.4) Inquiry
SHR213312 shRNA set against Human SELS(NM_203472.1) Inquiry
SHW001137 shRNA set against Chicken VIMP (NM_001024734) Inquiry
SHW010203 shRNA set against Danio rerio VIMP (NM_001045334) Inquiry
Cat.No. Product Name Price
CDCR303780 Human VIMP ORF Clone(NM_018445.4) Inquiry
CDFG001869 Human VIMP cDNA Clone(NM_018445.4) Inquiry
CDFG013563 Human VIMP cDNA Clone(NM_203472.1) Inquiry
CDFG013564 Human VIMP cDNA Clone(NM_203472.1) Inquiry
CDFR014784 Rat Sels cDNA Clone(NM_173120.2) Inquiry
MiUTR1H-09244 VIMP miRNA 3'UTR clone Inquiry
MiUTR1H-09245 VIMP miRNA 3'UTR clone Inquiry
MiUTR1M-05524 H47 miRNA 3'UTR clone Inquiry
MiUTR1R-06332 VIMP miRNA 3'UTR clone Inquiry
CDCB162612 Chicken VIMP ORF Clone (NM_001024734) Inquiry
CDCB171678 Danio rerio VIMP ORF Clone (NM_001045334) Inquiry
CDCB189350 Rabbit VIMP ORF clone (XM_008269811.1) Inquiry
CDCL115887 Mouse H47 ORF clone (NM_024439.3) Inquiry
CDCR327449 Human VIMP ORF Clone(NM_203472.1) Inquiry
CDCR381835 Rat Sels ORF Clone(NM_173120.2) Inquiry
CDCS414797 Human SELS ORF Clone (BC005840) Inquiry
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