Pages
Products

UNC45B


Official Full Name
unc-45 myosin chaperone B
Organism
Homo sapiens
Gene ID
146862
Background
This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Synonyms
CMYA4; MFM11; UNC45; CTRCT43; SMUNC45; UNC-45B

Cat.No. Product Name Price
SHH440536 shRNA set against Human UNC45B (NM_173167.2) Inquiry
SHH440540 shRNA set against Mouse UNC45B (NM_178680.4) Inquiry
SHH440544 shRNA set against Rat UNC45B (NM_001107028.1) Inquiry
SHL114686 shRNA set against Human UNC45B(NM_001033576.1) Inquiry
SHL114786 shRNA set against Human UNC45B(NM_173167.2) Inquiry
SHW015366 shRNA set against Danio rerio UNC45B (NM_153673) Inquiry
Cat.No. Product Name Price
CDFG010633 Human UNC45B cDNA Clone(NM_173167.2) Inquiry
CDFH020866 Human UNC45B cDNA Clone(NM_001033576.1) Inquiry
CDFR006740 Rat Unc45b cDNA Clone(NM_001107028.1) Inquiry
MiUTR1H-11013 UNC45B miRNA 3'UTR clone Inquiry
MiUTR1H-11014 UNC45B miRNA 3'UTR clone Inquiry
CDCB176841 Danio rerio UNC45B ORF Clone (NM_153673) Inquiry
CDCB190063 Rabbit UNC45B ORF clone (XM_008271126.1) Inquiry
CDCH098230 human UNC45B ORF clone (NM_001033576.1) Inquiry
CDCR275021 Mouse Unc45b ORF Clone(NM_178680.4) Inquiry
CDCR321736 Human UNC45B ORF Clone(NM_173167.2) Inquiry
CDCR373761 Rat Unc45b ORF Clone(NM_001107028.1) Inquiry
CDCS406841 Human UNC45B ORF Clone (BC101063) Inquiry
Quick Inquiry