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TWIST1


Official Full Name
twist family bHLH transcription factor 1
Organism
Homo sapiens
Gene ID
7291
Background
This gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. This gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism. [provided by RefSeq, Jul 2020]
Synonyms
CRS; CSO; SCS; ACS3; CRS1; BPES2; BPES3; SWCOS; TWIST; bHLHa38

Cat.No. Product Name Price
SHH438060 shRNA set against Human TWIST1 (NM_000474.3) Inquiry
SHH438064 shRNA set against Mouse TWIST1 (NM_011658.2) Inquiry
SHH438068 shRNA set against Rat TWIST1 (NM_053530.2) Inquiry
SHL107490 shRNA set against Human TWIST1(NM_000474.3) Inquiry
SHL107508 shRNA set against Mouse Twist1(NM_011658.2) Inquiry
SHL107526 shRNA set against Rat Twist1(NM_053530.2) Inquiry
SHW005247 shRNA set against Chicken TWIST1 (NM_204739) Inquiry
Cat.No. Product Name Price
CDFH020647 Human TWIST1 cDNA Clone(NM_000474.3) Inquiry
CDFR013255 Rat Twist1 cDNA Clone(NM_053530.2) Inquiry
MiUTR1H-10889 TWIST1 miRNA 3'UTR clone Inquiry
MiUTR1M-12322 TWIST1 miRNA 3'UTR clone Inquiry
MiUTR1R-08285 TWIST1 miRNA 3'UTR clone Inquiry
CDCB166722 Chicken TWIST1 ORF Clone (NM_204739) Inquiry
CDCH096886 Mouse Twist1 ORF clone (NM_011658.2) Inquiry
CDCR336558 Human TWIST1 ORF Clone(NM_000474.3) Inquiry
CDCR380172 Rat Twist1 ORF Clone(NM_053530.2) Inquiry
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