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TPBG

Official Full Name
trophoblast glycoprotein
Organism
Homo sapiens
GeneID
7162
Background
This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]
Synonyms
5T4; M6P1; 5T4AG; WAIF1;

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