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TOLLIP

Official Full Name
toll interacting protein
Organism
Homo sapiens
GeneID
54472
Background
This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Synonyms
IL-1RAcPIP;

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