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THPO


Official Full Name
thrombopoietin
Organism
Homo sapiens
Gene ID
7066
Background
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]
Synonyms
ML; TPO; MGDF; THC9; CAMT2; MKCSF; MPLLG; THCYT1

Cat.No. Product Name Price
SHH427000 shRNA set against Human THPO (NM_000460.2) Inquiry
SHH427004 shRNA set against Mouse THPO (NM_009379.3) Inquiry
SHH427008 shRNA set against Rat THPO (NM_031133.2) Inquiry
SHL069618 shRNA set against Mouse Thpo(NM_009379.3) Inquiry
SHL069708 shRNA set against Human THPO(NM_000460.2) Inquiry
SHW000117 shRNA set against Chicken THPO (NM_001001784) Inquiry
SHW013144 shRNA set against Danio rerio THPO (NM_001143753) Inquiry
Cat.No. Product Name Price
CDCB156922 Rat THPO ORF clone (NM_031133.1) Inquiry
CDFH019589 Human THPO cDNA Clone(NM_001177598.1) Inquiry
CDFH019588 Human THPO cDNA Clone(NM_001177597.1) Inquiry
CDFH019587 Human THPO cDNA Clone(NM_000460.2) Inquiry
MiUTR1H-10386 THPO miRNA 3'UTR clone Inquiry
CDCL186439 Human THPO ORF clone(NM_000460.2) Inquiry
MiUTR1M-11742 THPO miRNA 3'UTR clone Inquiry
CDCB161592 Chicken THPO ORF Clone (NM_001001784) Inquiry
CDCH090906 human THPO ORF clone (NM_001177598.1) Inquiry
CDCB183678 Rabbit THPO ORF clone (XM_008266590.1) Inquiry
CDCR242239 Mouse Thpo ORF Clone(NM_001173505.1) Inquiry
CDCR379595 Rat Thpo ORF Clone(NM_031133.2) Inquiry
CDCS419733 Human THPO ORF Clone (BC130322) Inquiry
CDCB174619 Danio rerio THPO ORF Clone (NM_001143753) Inquiry
CDCB156940 Cynomolgus THPO ORF clone (XM_001087664.1) Inquiry
CDCH090908 human THPO ORF clone (NM_001177597.1) Inquiry
CDCL186440 Mouse THPO ORF clone(NM_009379.3) Inquiry
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