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TDP1


Official Full Name
tyrosyl-DNA phosphodiesterase 1
Organism
Homo sapiens
Gene ID
55775
Background
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
Synonyms
ubald1; fam100a; fam100aa; zgc:92858

Cat.No. Product Name Price
SHH425288 shRNA set against Human TDP1 (NM_018319.3) Inquiry
SHH425292 shRNA set against Mouse TDP1 (NM_028354.4) Inquiry
SHH425296 shRNA set against Rat TDP1 (NM_001031657.1) Inquiry
SHL063566 shRNA set against Mouse Tdp1(NM_028354.4) Inquiry
SHL063666 shRNA set against Human TDP1(NM_001008744.1) Inquiry
SHL063712 shRNA set against Rat Tdp1(NM_001031657.1) Inquiry
Cat.No. Product Name Price
CDFG001719 Human TDP1 cDNA Clone(NM_018319.3) Inquiry
CDFH019405 Human TDP1 cDNA Clone(NM_001008744.1) Inquiry
CDFR004192 Rat Tdp1 cDNA Clone(NM_001031657.1) Inquiry
MiUTR1H-10298 TDP1 miRNA 3'UTR clone Inquiry
MiUTR1M-11652 TDP1 miRNA 3'UTR clone Inquiry
MiUTR1R-07955 TDP1 miRNA 3'UTR clone Inquiry
MiUTR3H-09037 TDP1 miRNA 3'UTR clone Inquiry
CDCB188148 Rabbit TDP1 ORF clone (XM_008271933.1) Inquiry
CDCH090016 Mouse Tdp1 ORF clone (NM_028354.4) Inquiry
CDCL186387 Human TDP1 ORF clone(NM_001008744.1) Inquiry
CDCR303508 Human TDP1 ORF Clone(NM_018319.3) Inquiry
CDCR371219 Rat Tdp1 ORF Clone(NM_001031657.1) Inquiry
CDCS406391 Human TDP1 ORF Clone (BC006083) Inquiry
Cat.No. Product Name Price
CC-1411 TDP1 Easy KO Kit Inquiry
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