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TTRAP

Official Full Name
tyrosyl-DNA phosphodiesterase 2
Organism
Homo sapiens
GeneID
51567
Background
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]
Synonyms
TDP2; EAP2; AD022; EAPII; TTRAP; hTDP2; dJ30M3.3;

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