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TRIM5


Official Full Name
tripartite motif containing 5
Organism
Homo sapiens
Gene ID
85363
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]
Synonyms
RNF88; TRIM5alpha

Cat.No. Product Name Price
SHH434852 shRNA set against Human TRIM5 (NM_033093.2) Inquiry
SHH434860 shRNA set against Rat TRIM5 (NM_001014023.1) Inquiry
Cat.No. Product Name Price
CDFR003159 Rat Trim5 cDNA Clone(NM_001014023.1) Inquiry
MiUTR1R-06409 TRIM5 miRNA 3'UTR clone Inquiry
MiUTR3H-10034 TRIM5 miRNA 3'UTR clone Inquiry
MiUTR3H-10035 TRIM5 miRNA 3'UTR clone Inquiry
CDCB180529 Rabbit TRIM5 ORF clone (XM_008258588.1) Inquiry
CDCR370176 Rat Trim5 ORF Clone(NM_001014023.1) Inquiry
CDCS416438 Human TRIM5 ORF Clone (BC021258) Inquiry
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