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TLE1


Official Full Name
TLE family member 1, transcriptional corepressor
Organism
Homo sapiens
Gene ID
7088
Background
Enables DNA-binding transcription factor binding activity; identical protein binding activity; and transcription corepressor activity. Involved in negative regulation of anoikis; negative regulation of signal transduction; and regulation of gene expression. Located in cytosol and nucleoplasm. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
ESG; ESG1; GRG1; TLE-1

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