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TIFA


Official Full Name
TRAF interacting protein with forkhead associated domain
Organism
Homo sapiens
Gene ID
92610
Background
This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. [provided by RefSeq, Jun 2018]
Synonyms
T2BP; T6BP; TIFAA

Cat.No. Product Name Price
SHH427264 shRNA set against Human TIFA (NM_052864.2) Inquiry
SHH427268 shRNA set against Mouse TIFA (NM_145133.3) Inquiry
SHH427272 shRNA set against Rat TIFA (NM_001014044.1) Inquiry
Cat.No. Product Name Price
CDCR314252 Human TIFA ORF Clone(NM_052864.2) Inquiry
CDFG006981 Human TIFA cDNA Clone(NM_052864.2) Inquiry
CDFR003180 Rat Tifa cDNA Clone(NM_001014044.1) Inquiry
MiUTR1H-10407 TIFA miRNA 3'UTR clone Inquiry
MiUTR1M-11467 TIFA miRNA 3'UTR clone Inquiry
MiUTR1R-03159 TIFA miRNA 3'UTR clone Inquiry
CDCB193164 Rabbit TIFA ORF clone (XM_008267477.1) Inquiry
CDCR370196 Rat Tifa ORF Clone(NM_001014044.1) Inquiry
CDCS416548 Human TIFA ORF Clone (BC014259) Inquiry
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