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TGF-BETA 2


Official Full Name
transforming growth factor beta receptor 2
Organism
Homo sapiens
Gene ID
7048
Background
The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
Synonyms
TGFBR2; AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TBRII; TBR-ii; TGFR-2; tbetaR-II; TGFbeta-RII

Cat.No. Product Name Price
SHH426404 shRNA set against Rat TGFB2 (NM_031131.1) Inquiry
SHH426396 shRNA set against Human TGFB2 (NM_003238.3) Inquiry
SHH426400 shRNA set against Mouse TGFB2 (NM_009367.3) Inquiry
SHL067608 shRNA set against Rat Tgfb2(NM_031131.1) Inquiry
SHL067662 shRNA set against Mouse Tgfb2(NM_009367.3) Inquiry
SHW001667 shRNA set against Chicken TGFB2 (NM_001031045) Inquiry
SHW015621 shRNA set against Danio rerio TGFB2 (NM_194385) Inquiry
Cat.No. Product Name Price
CDCB177096 Danio rerio TGFB2 ORF Clone (NM_194385) Inquiry
CDCB180457 Rabbit TGFB2 ORF clone (XM_008268050.1) Inquiry
CDCR379593 Rat Tgfb2 ORF Clone(NM_031131.1) Inquiry
CDFR012601 Rat Tgfb2 cDNA Clone(NM_031131.1) Inquiry
MiUTR1M-11706 TGFB2 miRNA 3'UTR clone Inquiry
MiUTR1R-07987 TGFB2 miRNA 3'UTR clone Inquiry
MiUTR3H-02282 TGFB2 miRNA 3'UTR clone Inquiry
CDCB156902 Cynomolgus TGFB2 ORF clone Inquiry
CDCB156912 Rat TGFB2 ORF clone (AF153013.1) Inquiry
CDCB163142 Chicken TGFB2 ORF Clone (NM_001031045) Inquiry
CDCL186412 Mouse TGFB2 ORF clone(NM_009367.3) Inquiry
CDCL186417 Human TGF-beta 2 ORF clone(NM_003238.3) Inquiry
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