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SPTLC1


Official Full Name
serine palmitoyltransferase long chain base subunit 1
Organism
Homo sapiens
Gene ID
10558
Background
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013]
Synonyms
HSN1; LBC1; LCB1; SPT1; SPTI; ALS27; HSAN1

Cat.No. Product Name Price
SHH417536 shRNA set against Human SPTLC1 (NM_006415.2) Inquiry
SHH417540 shRNA set against Mouse SPTLC1 (NM_009269.2) Inquiry
SHH417544 shRNA set against Rat SPTLC1 (NM_001108406.1) Inquiry
SHL031512 shRNA set against Human SPTLC1(NM_178324.1) Inquiry
SHL031530 shRNA set against Human SPTLC1(NM_006415.2) Inquiry
SHL031728 shRNA set against Mouse Sptlc1(NM_009269.2) Inquiry
SHW008562 shRNA set against Danio rerio SPTLC1 (NM_001020471) Inquiry
Cat.No. Product Name Price
CDFG011547 Human SPTLC1 cDNA Clone(NM_178324.1) Inquiry
CDFH018583 Human SPTLC1 cDNA Clone(NM_006415.2) Inquiry
CDFR008025 Rat Sptlc1 cDNA Clone(NM_001108406.1) Inquiry
MiUTR1H-09889 SPTLC1 miRNA 3'UTR clone Inquiry
MiUTR1H-09890 SPTLC1 miRNA 3'UTR clone Inquiry
MiUTR1M-11212 SPTLC1 miRNA 3'UTR clone Inquiry
CDCB170037 Danio rerio SPTLC1 ORF Clone (NM_001020471) Inquiry
CDCB191018 Rabbit SPTLC1 ORF clone (XM_008257932.1) Inquiry
CDCH085716 human SPTLC1 ORF clone (NM_178324.1) Inquiry
CDCH085740 Mouse Sptlc1 ORF clone (NM_009269.2) Inquiry
CDCR292852 Human SPTLC1 ORF Clone(NM_006415.2) Inquiry
CDCR375066 Rat Sptlc1 ORF Clone(NM_001108406.1) Inquiry
CDCS412725 Human SPTLC1 ORF Clone (BC007085) Inquiry
CDCS412726 Human SPTLC1 ORF Clone (BC068537) Inquiry
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