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SAFB


Official Full Name
scaffold attachment factor B
Organism
Homo sapiens
Gene ID
6294
Background
This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
Synonyms
HAP; HET; SAF-B; SAFB1; SAB-B1; SAF-B1

Cat.No. Product Name Price
SHH401480 shRNA set against Mouse SAFB (NM_001163300.1) Inquiry
SHH401484 shRNA set against Rat SAFB (NM_022394.1) Inquiry
SHR203684 shRNA set against Rat Safb(NM_022394.1) Inquiry
SHW018600 shRNA set against Danio rerio SAFB (NM_214683) Inquiry
Cat.No. Product Name Price
CDFG020246 Mouse Safb cDNA Clone(NM_001163300.1) Inquiry
CDFR011843 Rat Safb cDNA Clone(NM_022394.1) Inquiry
MiUTR1R-07158 SAFB miRNA 3'UTR clone Inquiry
MiUTR3H-05388 SAFB miRNA 3'UTR clone Inquiry
CDCB180075 Danio rerio SAFB ORF Clone (NM_214683) Inquiry
CDCB185134 Rabbit SAFB ORF clone (XM_008253140.1) Inquiry
CDCH076688 Mouse Safb ORF clone (NM_001163300.1) Inquiry
CDCH076692 human SAFB ORF clone (NM_001201340.1) Inquiry
CDCH076694 human SAFB ORF clone (NM_001201338.1) Inquiry
CDCR379002 Rat Safb ORF Clone(NM_022394.1) Inquiry
CDCS409537 Human SAFB ORF Clone (BC126219) Inquiry
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