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SPTA1


Official Full Name
spectrin alpha, erythrocytic 1
Organism
Homo sapiens
Gene ID
6708
Background
This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3. [provided by RefSeq, Aug 2017]
Synonyms
EL2; HPP; HS3; SPH3; SPTA

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LV26589L human SPTA1 (NM_003126) lentivirus particles Inquiry
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SHH417480 shRNA set against Human SPTA1 (NM_003126.2) Inquiry
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MiUTR1H-09883 SPTA1 miRNA 3'UTR clone Inquiry
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