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SPPL2B


Official Full Name
signal peptide peptidase like 2B
Organism
Homo sapiens
Gene ID
56928
Background
This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
IMP4; PSH4; PSL1; IMP-4

Cat.No. Product Name Price
SHH417144 shRNA set against Human SPPL2B (NM_152988.2) Inquiry
SHH417148 shRNA set against Rat SPPL2B (NM_001014200.1) Inquiry
SHL030294 shRNA set against Human SPPL2B(NM_001077238.1) Inquiry
SHL030323 shRNA set against Human SPPL2B(NM_152988.2) Inquiry
SHW001564 shRNA set against Chicken SPPL2B (NM_001030933) Inquiry
Cat.No. Product Name Price
CDFH018549 Human SPPL2B cDNA Clone(NM_001077238.1) Inquiry
CDFR003313 Rat Sppl2b cDNA Clone(NM_001014200.1) Inquiry
MiUTR1H-09867 SPPL2B miRNA 3'UTR clone Inquiry
MiUTR1H-09868 SPPL2B miRNA 3'UTR clone Inquiry
MiUTR1R-06629 SPPL2B miRNA 3'UTR clone Inquiry
CDCB163039 Chicken SPPL2B ORF Clone (NM_001030933) Inquiry
CDCL150172 Human SPPL2B ORF clone (NM_001077238.1) Inquiry
CDCR370333 Rat Sppl2b ORF Clone(NM_001014200.1) Inquiry
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