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SPG20


Official Full Name
spartin
Organism
Homo sapiens
Gene ID
23111
Background
This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]
Synonyms
SPART; SPG20; TAHCCP1

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CDCH085226 Mouse Spg20 ORF clone (NM_001144988.1) Inquiry
CDCR238002 Mouse Spg20 ORF Clone(NM_001144987.1) Inquiry
CDCR266550 Mouse Spg20 ORF Clone(NM_144895.2) Inquiry
CDCR351167 Human SPG20 ORF Clone(NM_001142294.1) Inquiry
CDCR351169 Human SPG20 ORF Clone(NM_001142295.1) Inquiry
CDCR351172 Human SPG20 ORF Clone(NM_001142296.1) Inquiry
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