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SOCS1


Official Full Name
suppressor of cytokine signaling 1
Organism
Homo sapiens
Gene ID
8651
Background
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
Synonyms
JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; TIP-3; AISIMD; SOCS-1

Cat.No. Product Name Price
SHH414944 shRNA set against Mouse SOCS1 (NM_009896.2) Inquiry
SHH414948 shRNA set against Rat SOCS1 (NM_145879.1) Inquiry
SHL024222 shRNA set against Human SOCS1(NM_003745.1) Inquiry
SHL024240 shRNA set against Rat Socs1(NM_145879.1) Inquiry
SHL024294 shRNA set against Mouse Socs1(NM_009896.2) Inquiry
SHW002823 shRNA set against Chicken SOCS1 (NM_001137648) Inquiry
Cat.No. Product Name Price
CDCH084368 Mouse Socs1 ORF clone (NM_009896.2) Inquiry
CDCR381618 Rat Socs1 ORF Clone(NM_145879.1) Inquiry
CDFH018305 Human SOCS1 cDNA Clone(NM_003745.1) Inquiry
CDFR014531 Rat Socs1 cDNA Clone(NM_145879.1) Inquiry
MiUTR1H-09730 SOCS1 miRNA 3'UTR clone Inquiry
MiUTR1M-11075 SOCS1 miRNA 3'UTR clone Inquiry
MiUTR1R-07609 SOCS1 miRNA 3'UTR clone Inquiry
CDCB164298 Chicken SOCS1 ORF Clone (NM_001137648) Inquiry
CDCB193994 Rabbit SOCS1 ORF clone (XM_008257720.1) Inquiry
CDCH084366 human SOCS1 ORF clone (NM_003745.1) Inquiry
CDCL186255 Human SOCS1 ORF clone(NM_024509.1) Inquiry
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