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SMAD1


Official Full Name
SMAD family member 1
Organism
Homo sapiens
Gene ID
4086
Background
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Synonyms
BSP1; JV41; BSP-1; JV4-1; MADH1; MADR1

Cat.No. Product Name Price
SHH412952 shRNA set against Mouse Smad1 (NM_008539.3) Inquiry
SHH077501 shRNA set against Mouse Gars(NM_180678.3) Inquiry
SHH077519 shRNA set against Human GARS(NM_002047.2) Inquiry
SHH299369 shRNA set against Human GARS (NM_002047.2) Inquiry
SHH299373 shRNA set against Mouse GARS (NM_180678.3) Inquiry
SHH412948 shRNA set against Human Smad1 (NM_005900.2) Inquiry
SHH412956 shRNA set against Rat Smad1 (NM_013130.2) Inquiry
SHL014886 shRNA set against Rat Smad1(NM_013130.2) Inquiry
SHL015038 shRNA set against Human SMAD1(NM_001003688.1) Inquiry
SHL015056 shRNA set against Mouse Smad1(NM_008539.3) Inquiry
SHL015074 shRNA set against Human SMAD1(NM_005900.2) Inquiry
SHW002097 shRNA set against Chicken GARS (NM_001031510) Inquiry
SHW003436 shRNA set against Chicken SMAD1 (NM_001201455) Inquiry
SHW014822 shRNA set against Danio rerio SMAD1 (NM_131356) Inquiry
Cat.No. Product Name Price
CDCS406168 Human SMAD1 ORF Clone (BC001878) Inquiry
MiUTR1M-04935 GARS miRNA 3'UTR clone Inquiry
MiUTR1H-09635 SMAD1 miRNA 3'UTR clone Inquiry
MiUTR1H-09634 SMAD1 miRNA 3'UTR clone Inquiry
MiUTR1H-03956 GARS miRNA 3'UTR clone Inquiry
CDFR010929 Rat Smad1 cDNA Clone(NM_013130.2) Inquiry
CDFH018109 Human SMAD1 cDNA Clone(NM_005900.2) Inquiry
CDFH018108 Human SMAD1 cDNA Clone(NM_001003688.1) Inquiry
CDFH007370 Human GARS cDNA Clone(NM_002047.2) Inquiry
CDFH007369 Human GARS cDNA Clone(NM_002047.2) Inquiry
MiUTR1M-10975 SMAD1 miRNA 3'UTR clone Inquiry
MiUTR1R-07550 SMAD1 miRNA 3'UTR clone Inquiry
CDCS410579 Human GARS ORF Clone (BC000065) Inquiry
CDCR291562 Human SMAD1 ORF Clone(NM_005900.2) Inquiry
CDCL186232 Mouse Smad1 ORF clone(NM_008539.3) Inquiry
CDCL186231 Human Smad1 ORF clone(NM_001003688.1) Inquiry
CDCL110659 Human Gars ORF clone (NM_180678.3) Inquiry
CDCL110651 Human GARS ORF clone (NM_002047.2) Inquiry
CDCB194718 Rabbit GARS ORF clone (XM_008261599.1) Inquiry
CDCB192731 Rabbit SMAD1 ORF clone (XM_008267392.1) Inquiry
CDCB176297 Danio rerio SMAD1 ORF Clone (NM_131356) Inquiry
CDCB164911 Chicken SMAD1 ORF Clone (NM_001201455) Inquiry
CDCR377876 Rat Smad1 ORF Clone(NM_013130.2) Inquiry
CDCB163572 Chicken GARS ORF Clone (NM_001031510) Inquiry
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