Pages
Products

SLC12A3


Official Full Name
solute carrier family 12 member 3
Organism
Homo sapiens
Gene ID
6559
Background
This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
NCC; TSC; NCCT

Cat.No. Product Name Price
SHH408324 shRNA set against Human Slc12a3 (NM_000339.2) Inquiry
SHH408329 shRNA set against Mouse Slc12a3 (NM_019415.2) Inquiry
SHH408332 shRNA set against Rat Slc12a3 (NM_019345.3) Inquiry
SHR228174 shRNA set against Rat Slc12a3(NM_019345.3) Inquiry
SHW010018 shRNA set against Danio rerio SLC12A3 (NM_001045080) Inquiry
Cat.No. Product Name Price
CDFH017660 Human SLC12A3 cDNA Clone(NM_001126107.1) Inquiry
CDFH017661 Human SLC12A3 cDNA Clone(NM_001126108.1) Inquiry
CDFR011585 Rat Slc12a3 cDNA Clone(NM_019345.3) Inquiry
MiUTR1R-07365 SLC12A3 miRNA 3'UTR clone Inquiry
CDCB171493 Danio rerio SLC12A3 ORF Clone (NM_001045080) Inquiry
CDCB180726 Rabbit SLC12A3 ORF clone (NM_001082649.1) Inquiry
CDCH080768 human SLC12A3 ORF clone (NM_000339.2) Inquiry
CDCH080770 human SLC12A3 ORF clone (NM_001126107.1) Inquiry
CDCH080772 human SLC12A3 ORF clone (NM_001126108.1) Inquiry
CDCR378632 Rat Slc12a3 ORF Clone(NM_019345.3) Inquiry
Quick Inquiry