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SAA1


Official Full Name
serum amyloid A1
Organism
Homo sapiens
Gene ID
6288
Background
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Jul 2020]
Synonyms
SAA; PIG4; SAA2; TP53I4

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AD14187Z Human SAA1 adenoviral particles Inquiry
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SHH401388 shRNA set against Human SAA1 (NM_000331.4) Inquiry
SHH401392 shRNA set against Mouse SAA1 (NM_009117.3) Inquiry
SHR203376 shRNA set against Mouse Saa1(NM_009117.3) Inquiry
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CDFH016862 Human SAA1 cDNA Clone(NM_001178006.1) Inquiry
MiUTR1M-10376 SAA1 miRNA 3'UTR clone Inquiry
MiUTR4H-TG07769 SAA1 miRNA 3'UTR clone Inquiry
CDCB160429 Human SAA1 ORF clone (NM_000331.3) Inquiry
CDCH076636 Mouse Saa1 ORF clone (NM_009117.3) Inquiry
CDCR357188 Human SAA1 ORF Clone(NM_001178006.1) Inquiry
CDCS405587 Human SAA1 ORF Clone (BC007022) Inquiry
CDCS419461 Human SAA1 ORF Clone (BC020795) Inquiry
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CC-1254 SAA1 Easy KO Kit (Mouse) Inquiry
CC-1255 SAA1 Easy KO Kit (Human) Inquiry
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