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RTKN


Official Full Name
rhotekin
Organism
Homo sapiens
Gene ID
6242
Background
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
RTKN-1

Cat.No. Product Name Price
SHH400476 shRNA set against Human RTKN (NM_033046.2) Inquiry
SHH400480 shRNA set against Mouse RTKN (NM_133641.2) Inquiry
SHH400484 shRNA set against Rat RTKN (NM_184046.1) Inquiry
SHR200254 shRNA set against Rat Rtkn(NM_184046.1) Inquiry
SHR200434 shRNA set against Human RTKN(NM_001015056.1) Inquiry
SHR200488 shRNA set against Human RTKN(NM_001015055.1) Inquiry
SHR200506 shRNA set against Human RTKN(NM_033046.2) Inquiry
Cat.No. Product Name Price
MiUTR3H-04843 RTKN miRNA 3'UTR clone Inquiry
MiUTR1H-09063 RTKN miRNA 3'UTR clone Inquiry
MiUTR1H-09062 RTKN miRNA 3'UTR clone Inquiry
CDFR015112 Rat Rtkn cDNA Clone(NM_184046.1) Inquiry
CDFH016769 Human RTKN cDNA Clone(NM_001015056.1) Inquiry
CDFH016768 Human RTKN cDNA Clone(NM_001015055.1) Inquiry
CDFG006567 Human RTKN cDNA Clone(NM_033046.2) Inquiry
MiUTR1R-07133 RTKN miRNA 3'UTR clone Inquiry
CDCS406572 Human RTKN ORF Clone (BC004558) Inquiry
CDCS406571 Human RTKN ORF Clone (BC017727) Inquiry
CDCR382103 Rat Rtkn ORF Clone(NM_184046.1) Inquiry
CDCR341697 Human RTKN ORF Clone(NM_001015055.1) Inquiry
CDCR313313 Human RTKN ORF Clone(NM_033046.2) Inquiry
CDCH076182 Mouse Rtkn ORF clone (NM_001136227.1) Inquiry
CDCH076174 human RTKN ORF clone (NM_001015056.1) Inquiry
CDCB188234 Rabbit RTKN ORF clone (XM_008254713.1) Inquiry
CDCR382902 Mouse Rtkn ORF Clone(NM_009106.2) Inquiry
CDCB158212 Human RTKN ORF clone (BC004558) Inquiry
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