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RIN2


Official Full Name
Ras and Rab interactor 2
Organism
Homo sapiens
Gene ID
54453
Background
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Synonyms
MACS; RASSF4

Cat.No. Product Name Price
SHH395892 shRNA set against Human RIN2 (NM_018993.3) Inquiry
SHH395896 shRNA set against Mouse RIN2 (NM_028724.4) Inquiry
SHH395900 shRNA set against Rat RIN2 (NM_001107786.1) Inquiry
Cat.No. Product Name Price
CDFR007413 Rat Rin2 cDNA Clone(NM_001107786.1) Inquiry
MiUTR3H-11094 RIN2 miRNA 3'UTR clone Inquiry
CDCB190579 Rabbit RIN2 ORF clone (XM_008256343.1) Inquiry
CDCH071978 Mouse Rin2 ORF clone (NM_028724.4) Inquiry
CDCR374461 Rat Rin2 ORF Clone(NM_001107786.1) Inquiry
CDCS419390 Human RIN2 ORF Clone (BC128065) Inquiry
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