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RGS14


Official Full Name
regulator of G protein signaling 14
Organism
Homo sapiens
Gene ID
10636
Background
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Synonyms
BSC; BSC2; CCC1; BSC-2; KILQS; NKCC1; hNKCC1; PPP1R141

Cat.No. Product Name Price
SHH394864 shRNA set against Human RGS14 (NM_006480.4) Inquiry
SHH394868 shRNA set against Mouse RGS14 (NM_016758.3) Inquiry
SHH394872 shRNA set against Rat RGS14 (NM_053764.1) Inquiry
SHR178980 shRNA set against Human RGS14(NM_006480.4) Inquiry
SHR179016 shRNA set against Rat Rgs14(NM_053764.1) Inquiry
SHW017338 shRNA set against Danio rerio RGS14A (NM_201304) Inquiry
Cat.No. Product Name Price
CDCH068444 human PRR21 ORF clone (NM_001080835.1) Inquiry
CDFH015240 Human PRR21 cDNA Clone(NM_001080835.1) Inquiry
CDFH016259 Human RGS14 cDNA Clone(NM_006480.4) Inquiry
CDFH016260 Human RGS14 cDNA Clone(NM_006480.4) Inquiry
CDFR013512 Rat Rgs14 cDNA Clone(NM_053764.1) Inquiry
MiUTR1H-05845 PRR21 miRNA 3'UTR clone Inquiry
MiUTR1R-06924 RGS14 miRNA 3'UTR clone Inquiry
MiUTR3H-05049 RGS14 miRNA 3'UTR clone Inquiry
CDCB178813 Danio rerio RGS14A ORF Clone (NM_201304) Inquiry
CDCB187397 Rabbit RGS14 ORF clone (XM_008255464.1) Inquiry
CDCR292993 Human RGS14 ORF Clone(NM_006480.4) Inquiry
CDCR380544 Rat Rgs14 ORF Clone(NM_053764.1) Inquiry
CDCS412767 Human RGS14 ORF Clone (BC014094) Inquiry
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