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RASD2


Official Full Name
RASD family member 2
Organism
Homo sapiens
Gene ID
23551
Background
This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016]
Synonyms
Rhes; TEM2

Cat.No. Product Name Price
SHH389944 shRNA set against Human RASD2 (NM_014310.3) Inquiry
SHH389952 shRNA set against Rat RASD2 (NM_133568.1) Inquiry
SHR165984 shRNA set against Rat Rasd2(NM_133568.1) Inquiry
SHR166033 shRNA set against Human RASD2(NM_014310.3) Inquiry
Cat.No. Product Name Price
CDFH015939 Human RASD2 cDNA Clone(NM_014310.3) Inquiry
CDFH015940 Human RASD2 cDNA Clone(NM_014310.3) Inquiry
CDFR014085 Rat Rasd2 cDNA Clone(NM_133568.1) Inquiry
MiUTR1H-08641 RASD2 miRNA 3'UTR clone Inquiry
MiUTR1R-06321 RASD2 miRNA 3'UTR clone Inquiry
CDCB185437 Rabbit RASD2 ORF clone (XM_002724067.2) Inquiry
CDCR297296 Human RASD2 ORF Clone(NM_014310.3) Inquiry
CDCR381140 Rat Rasd2 ORF Clone(NM_133568.1) Inquiry
CDCS413570 Human RASD2 ORF Clone (BC013419) Inquiry
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