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RPL7


Official Full Name
ribosomal protein L7
Organism
Homo sapiens
Gene ID
6129
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Synonyms
L7; uL30; humL7-1

Cat.No. Product Name Price
SHH398788 shRNA set against Mouse RPL7 (NM_011291.5) Inquiry
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SHR195430 shRNA set against Human RPL7(NM_000971.3) Inquiry
SHW000431 shRNA set against Chicken RPL7 (NM_001006345) Inquiry
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Cat.No. Product Name Price
CDCH075380 human RPL7 ORF clone (NM_000971.3) Inquiry
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CDCB161906 Chicken RPL7 ORF Clone (NM_001006345) Inquiry
CDCB180070 Danio rerio RPL7 ORF Clone (NM_213644) Inquiry
CDCB193708 Rabbit RPL7 ORF clone (XM_002710635.2) Inquiry
CDCR372311 Rat Rpl7 ORF Clone(NM_001100534.1) Inquiry
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