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REN

Official Full Name
renin
Background
Prorenin is a glycosylated aspartic protease that consists of 2?homologouslobes and is the precursor of renin. Renin activates the renin-angiotensinsystem by cleaving angiotensinogen, produced by the liver, to yield angiotensinI, which is further converted into angiotensin II by ACE, theangiotensin-converting enzyme primarily within the capillaries of the lungs. Ithas been reported that the levels of circulating prorenin (but not renin) areincreased in diabetic subjects.
Synonyms
Prorenin; REN; renin; angiotensinogenase; renin precursor, renal; angiotensin-forming enzyme; HNFJ2; FLJ10761

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