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RAPGEF4

Official Full Name
Rap guanine nucleotide exchange factor (GEF) 4
Background
EPAC1 and EPAC2 (exchange proteins activated by cyclic AMP) are guanine nucleotide exchange factors (GEFs) that catalyze the exchange of GDP for GTP, activating Rap1 and Rap2 small GTPases. Rap activation by EPAC is cAMP-dependent and mediates cAMP signal
Synonyms
RAPGEF4; Rap guanine nucleotide exchange factor (GEF) 4; rap guanine nucleotide exchange factor 4; exchange protein directly activated by cAMP 2; cAMP GEFII; cAMP regulated guanine nucleotide exchange factor; cAMP regulated guanine nucleotide exchange factor II; CGEF2; EPAC 2; putative protein product of Nbla00496; exchange factor directly activated by cAMP 2; RAP guanine-nucleotide-exchange factor (GEF) 4; cAMP-regulated guanine nucleotide exchange factor II; EPAC2; Nbla00496; CAMP-GEFII

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