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PRKAB2


Official Full Name
protein kinase AMP-activated non-catalytic subunit beta 2
Organism
Homo sapiens
Gene ID
5565
Background
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
Synonyms
RGD1562373

Cat.No. Product Name Price
SHH382660 shRNA set against Human PRKAB2 (NM_005399.3) Inquiry
SHH382664 shRNA set against Mouse PRKAB2 (NM_182997.2) Inquiry
SHH382668 shRNA set against Rat PRKAB2 (NM_022627.2) Inquiry
SHR139656 shRNA set against Mouse Prkab2(NM_182997.2) Inquiry
SHR139746 shRNA set against Human PRKAB2(NM_005399.3) Inquiry
SHW002396 shRNA set against Chicken PRKAB2 (NM_001044662) Inquiry
SHW012992 shRNA set against Danio rerio PRKAB2 (NM_001130633) Inquiry
Cat.No. Product Name Price
CDCR379105 Rat Prkab2 ORF Clone(NM_022627.2) Inquiry
CDFH015094 Human PRKAB2 cDNA Clone(NM_005399.3) Inquiry
MiUTR1H-08257 PRKAB2 miRNA 3'UTR clone Inquiry
MiUTR1M-09571 PRKAB2 miRNA 3'UTR clone Inquiry
CDCB160298 Human PRKAB2 ORF clone (NM_005399) Inquiry
CDCB163871 Chicken PRKAB2 ORF Clone (NM_001044662) Inquiry
CDCB174467 Danio rerio PRKAB2 ORF Clone (NM_001130633) Inquiry
CDCB193385 Rabbit PRKAB2 ORF clone (XM_002715664.2) Inquiry
CDCH067728 Mouse Prkab2 ORF clone (NM_182997.2) Inquiry
CDCR290249 Human PRKAB2 ORF Clone(NM_005399.3) Inquiry
CDCS412237 Human PRKAB2 ORF Clone (BC053610) Inquiry
Cat.No. Product Name Price
CC-1134 PRKAB2 Easy KO Kit Inquiry
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