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PCSK6


Official Full Name
proprotein convertase subtilisin/kexin type 6
Organism
Homo sapiens
Gene ID
5046
Background
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2014]
Synonyms
SPC4; PACE4

Cat.No. Product Name Price
SHH372036 shRNA set against Human PCSK6 (NM_002570.3) Inquiry
SHH372040 shRNA set against Rat PCSK6 (NM_012999.1) Inquiry
SHR097836 shRNA set against Human PCSK6(NM_138322.2) Inquiry
SHR098070 shRNA set against Human PCSK6(NM_138319.2) Inquiry
SHR098088 shRNA set against Human PCSK6(NM_002570.3) Inquiry
SHR098106 shRNA set against Human PCSK6(NM_138320.1) Inquiry
SHR098124 shRNA set against Human PCSK6(NM_138323.1) Inquiry
SHR098142 shRNA set against Human PCSK6(NM_138325.2) Inquiry
SHR098160 shRNA set against Human PCSK6(NM_138321.1) Inquiry
SHR098170 shRNA set against Rat Pcsk6(NM_012999.1) Inquiry
SHR098238 shRNA set against Human PCSK6(NM_138324.1) Inquiry
Cat.No. Product Name Price
CDFG007872 Human PCSK6 cDNA Clone(NM_138321.1) Inquiry
MiUTR1R-05691 PCSK6 miRNA 3'UTR clone Inquiry
MiUTR1H-07688 PCSK6 miRNA 3'UTR clone Inquiry
MiUTR1H-07687 PCSK6 miRNA 3'UTR clone Inquiry
MiUTR1H-07686 PCSK6 miRNA 3'UTR clone Inquiry
MiUTR1H-07685 PCSK6 miRNA 3'UTR clone Inquiry
MiUTR1H-07684 PCSK6 miRNA 3'UTR clone Inquiry
MiUTR1H-07683 PCSK6 miRNA 3'UTR clone Inquiry
CDFR010806 Rat Pcsk6 cDNA Clone(NM_012999.1) Inquiry
CDFL010032 Mouse Pcsk6 cDNA Clone(NM_011048.1) Inquiry
CDFH013864 Human PCSK6 cDNA Clone(NM_002570.3) Inquiry
CDFG007875 Human PCSK6 cDNA Clone(NM_138324.1) Inquiry
CDFG007874 Human PCSK6 cDNA Clone(NM_138325.2) Inquiry
CDFG007873 Human PCSK6 cDNA Clone(NM_138323.1) Inquiry
MiUTR3H-01662 PCSK6 miRNA 3'UTR clone Inquiry
CDFG007871 Human PCSK6 cDNA Clone(NM_138322.2) Inquiry
CDFG007870 Human PCSK6 cDNA Clone(NM_138320.1) Inquiry
CDFG007869 Human PCSK6 cDNA Clone(NM_138319.2) Inquiry
CDCR283535 Human PCSK6 ORF Clone(NM_002570.3) Inquiry
CDCL147097 Mouse PCSK6 ORF clone (NM_138319.2) Inquiry
MiUTR3H-01657 PCSK6 miRNA 3'UTR clone Inquiry
CDCR377883 Rat Pcsk6 ORF Clone(NM_012999.1) Inquiry
CDCL147099 Human PCSK6 ORF clone (NM_138325.2) Inquiry
CDCL147095 Human PCSK6 ORF clone (NM_138320.1) Inquiry
CDCL147093 Human PCSK6 ORF clone (NM_138321.1) Inquiry
CDCL147091 Human PCSK6 ORF clone (NM_138322.2) Inquiry
CDCL147089 Mouse PCSK6 ORF clone (NM_138323.1) Inquiry
CDCL147087 Human PCSK6 ORF clone (NM_138324.1) Inquiry
CDCL147085 Human Pcsk6 ORF clone (NM_011048.1) Inquiry
CDCB189513 Rabbit PCSK6 ORF clone (XM_008269785.1) Inquiry
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