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PTPN21


Official Full Name
protein tyrosine phosphatase non-receptor type 21
Organism
Homo sapiens
Gene ID
11099
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]
Synonyms
PTPD1; PTPRL10

Cat.No. Product Name Price
SHH386528 shRNA set against Mouse PTPN21 (NM_011877.2) Inquiry
SHH386524 shRNA set against Human PTPN21 (NM_007039.3) Inquiry
SHH386532 shRNA set against Rat PTPN21 (NM_133545.1) Inquiry
SHR152104 shRNA set against Rat Ptpn21(NM_133545.1) Inquiry
SHR152110 shRNA set against Human PTPN21(NM_007039.3) Inquiry
Cat.No. Product Name Price
CDFR014064 Rat Ptpn21 cDNA Clone(NM_133545.1) Inquiry
MiUTR1H-08465 PTPN21 miRNA 3'UTR clone Inquiry
MiUTR1R-06201 PTPN21 miRNA 3'UTR clone Inquiry
CDCB186796 Rabbit PTPN21 ORF clone (XM_002719612.2) Inquiry
CDCH069734 human PTPN21 ORF clone (NM_007039.3) Inquiry
CDCH069738 Mouse Ptpn21 ORF clone (NM_001146199.1) Inquiry
CDCR251500 Mouse Ptpn21 ORF Clone(NM_011877.2) Inquiry
CDCR381119 Rat Ptpn21 ORF Clone(NM_133545.1) Inquiry
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