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PTP4A2


Official Full Name
protein tyrosine phosphatase 4A2
Organism
Homo sapiens
Gene ID
8073
Background
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
Synonyms
HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b

Cat.No. Product Name Price
SHH386336 shRNA set against Rat Ptp4a2 (NM_053475.1) Inquiry
SHR151536 shRNA set against Rat Ptp4a2(NM_053475.1) Inquiry
SHH386328 shRNA set against Human Ptp4a2 (NM_080391.3) Inquiry
SHH386335 shRNA set against Mouse Ptp4a2 (NM_008974.4) Inquiry
Cat.No. Product Name Price
CDCB159555 Human PTP4A2 ORF clone (BC070182) Inquiry
CDFR013206 Rat Ptp4a2 cDNA Clone(NM_053475.1) Inquiry
MiUTR1R-06195 PTP4A2 miRNA 3'UTR clone Inquiry
MiUTR3H-04234 PTP4A2 miRNA 3'UTR clone Inquiry
SKO0725 PTP4A2 Validated sgRNA vector Inquiry
CDCB187213 Rabbit PTP4A2 ORF clone (XM_002720636.2) Inquiry
CDCH067938 human PTP4A2 ORF clone (NM_001195101.1) Inquiry
CDCH067942 human PTP4A2 ORF clone (NM_001195100.1) Inquiry
CDCH395844 Mouse PTP4A2 ORF clone(NM_008974.4) Inquiry
CDCR240799 Mouse Ptp4a2 ORF Clone(NM_001164745.1) Inquiry
CDCR380293 Rat Ptp4a2 ORF Clone(NM_053475.1) Inquiry
CDCS409306 Human PTP4A2 ORF Clone (BC070182) Inquiry
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