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PSPC1


Official Full Name
paraspeckle component 1
Organism
Homo sapiens
Gene ID
55269
Background
This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified. [provided by RefSeq, Aug 2011]
Synonyms
PSP1

Cat.No. Product Name Price
SHH385652 shRNA set against Human PSPC1 (NM_001042414.2) Inquiry
SHH385656 shRNA set against Mouse PSPC1 (NM_025682.3) Inquiry
SHH385660 shRNA set against Rat PSPC1 (NM_001025672.1) Inquiry
SHR149286 shRNA set against Rat Pspc1(NM_001025672.1) Inquiry
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Cat.No. Product Name Price
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CDCB171622 Danio rerio PSPC1 ORF Clone (NM_001045258) Inquiry
CDCB182853 Rabbit PSPC1 ORF clone (XM_008259953.1) Inquiry
CDCR371004 Rat Pspc1 ORF Clone(NM_001025672.1) Inquiry
CDCS407083 Human PSPC1 ORF Clone (BC014184) Inquiry
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