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PSMB10


Official Full Name
proteasome 20S subunit beta 10
Organism
Homo sapiens
Gene ID
5699
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]
Synonyms
LMP10; MECL1; IMD121; PRAAS5; beta2i

Cat.No. Product Name Price
SHH385144 shRNA set against Human PSMB10 (NM_002801.3) Inquiry
SHH385148 shRNA set against Mouse PSMB10 (NM_013640.3) Inquiry
SHH385152 shRNA set against Rat PSMB10 (NM_001025637.1) Inquiry
SHR147288 shRNA set against Rat Psmb10(NM_001025637.1) Inquiry
SHW015090 shRNA set against Danio rerio PSMB10 (NM_131677) Inquiry
Cat.No. Product Name Price
CDFR003995 Rat Psmb10 cDNA Clone(NM_001025637.1) Inquiry
MiUTR1R-06142 PSMB10 miRNA 3'UTR clone Inquiry
MiUTR3H-01870 PSMB10 miRNA 3'UTR clone Inquiry
SKO0717 PSMB10 Validated sgRNA vector Inquiry
CDCB176565 Danio rerio PSMB10 ORF Clone (NM_131677) Inquiry
CDCB185808 Rabbit PSMB10 ORF clone (XM_002711627.2) Inquiry
CDCR370969 Rat Psmb10 ORF Clone(NM_001025637.1) Inquiry
CDCS410968 Human PSMB10 ORF Clone (BC017198) Inquiry
CDCS410969 Human PSMB10 ORF Clone (BC052369) Inquiry
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