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PRKCE


Official Full Name
protein kinase C epsilon
Organism
Homo sapiens
Gene ID
5581
Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
Synonyms
PKCE; nPKC-epsilon

Cat.No. Product Name Price
SHH382832 shRNA set against Human PRKCE (NM_005400.2) Inquiry
SHH382836 shRNA set against Mouse PRKCE (NM_011104.3) Inquiry
Cat.No. Product Name Price
CDFH015121 Human PRKCE cDNA Clone(NM_005400.2) Inquiry
CDFH015122 Human PRKCE cDNA Clone(NM_005400.2) Inquiry
CDFL010778 Mouse Prkce cDNA Clone(NM_011104.3) Inquiry
MiUTR1H-08274 PRKCE miRNA 3'UTR clone Inquiry
CDCB180298 Rabbit PRKCE ORF clone (NM_001082274.1) Inquiry
CDCL185827 Mouse PRKCE ORF clone(NM_011104.3) Inquiry
CDCS412238 Human PRKCE ORF Clone (BC109033) Inquiry
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