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PPP1CA


Official Full Name
protein phosphatase 1 catalytic subunit alpha
Organism
Homo sapiens
Gene ID
5499
Background
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). This broadly expressed gene encodes the alpha subunit of the PP1 complex that associates with over 200 regulatory proteins to form holoenzymes which dephosphorylate their biological targets with high specificity. PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies suggest that PP1 is an important regulator of cardiac function and that PP1 deregulation is implicated in diabetes and multiple types of cancer. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2020]
Synonyms
PP1A; PP-1A; PPP1A; PP1alpha

Cat.No. Product Name Price
SHH380948 shRNA set against Human PPP1CA (NM_002708.3) Inquiry
SHH380952 shRNA set against Mouse PPP1CA (NM_031868.2) Inquiry
SHH380956 shRNA set against Rat PPP1CA (NM_031527.1) Inquiry
SHR132756 shRNA set against Human PPP1CA(NM_002708.3) Inquiry
SHR132774 shRNA set against Human PPP1CA(NM_206873.1) Inquiry
SHR132810 shRNA set against Human PPP1CA(NM_001008709.1) Inquiry
SHR132828 shRNA set against Rat Ppp1ca(NM_031527.1) Inquiry
SHR132960 shRNA set against Mouse Ppp1ca(NM_031868.2) Inquiry
Cat.No. Product Name Price
CDFG013606 Human PPP1CA cDNA Clone(NM_206873.1) Inquiry
CDFH014873 Human PPP1CA cDNA Clone(NM_001008709.1) Inquiry
CDFH014874 Human PPP1CA cDNA Clone(NM_002708.3) Inquiry
CDFR012687 Rat Ppp1ca cDNA Clone(NM_031527.1) Inquiry
MiUTR1H-08169 PPP1CA miRNA 3'UTR clone Inquiry
MiUTR1H-08170 PPP1CA miRNA 3'UTR clone Inquiry
MiUTR1H-08171 PPP1CA miRNA 3'UTR clone Inquiry
MiUTR1M-09484 PPP1CA miRNA 3'UTR clone Inquiry
MiUTR1R-05999 PPP1CA miRNA 3'UTR clone Inquiry
CDCB180247 Rabbit PPP1CA ORF clone (NM_001101706.1) Inquiry
CDCH066738 human PPP1CA ORF clone (NM_001008709.1) Inquiry
CDCH066740 human PPP1CA ORF clone (NM_206873.1) Inquiry
CDCL185789 Mouse PPP1CA ORF clone(NM_031868.2) Inquiry
CDCR379720 Rat Ppp1ca ORF Clone(NM_031527.1) Inquiry
CDCS406386 Human PPP1CA ORF Clone (BC001888) Inquiry
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