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POLH


Official Full Name
DNA polymerase eta
Organism
Homo sapiens
Gene ID
5429
Background
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Synonyms
XPV; XP-V; RAD30; RAD30A

Cat.No. Product Name Price
SHH379244 shRNA set against Rat POLH (NM_001108204.1) Inquiry
SHH379236 shRNA set against Human POLH (NM_006502.2) Inquiry
SHH379240 shRNA set against Mouse POLH (NM_030715.3) Inquiry
SHR126722 shRNA set against Mouse Polh(NM_030715.3) Inquiry
SHW000030 shRNA set against Chicken POLH (NM_001001304) Inquiry
SHW009619 shRNA set against Danio rerio POLH (NM_001040247) Inquiry
Cat.No. Product Name Price
CDCB161505 Chicken POLH ORF Clone (NM_001001304) Inquiry
CDCR374885 Rat Polh ORF Clone(NM_001108204.1) Inquiry
CDFL010529 Mouse Polh cDNA Clone(NM_030715.3) Inquiry
CDFR007846 Rat Polh cDNA Clone(NM_001108204.1) Inquiry
MiUTR1M-09394 POLH miRNA 3'UTR clone Inquiry
SKO0159 POLH Validated sgRNA vector Inquiry
CDCB171094 Danio rerio POLH ORF Clone (NM_001040247) Inquiry
CDCB183414 Rabbit POLH ORF clone (XM_002714695.2) Inquiry
CDCR263682 Mouse Polh ORF Clone(NM_030715.3) Inquiry
CDCS412774 Human POLH ORF Clone (BC015742) Inquiry
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