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PLAU


Official Full Name
plasminogen activator, urokinase
Organism
Homo sapiens
Gene ID
5328
Background
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Synonyms
ATF; QPD; UPA; URK; u-PA; BDPLT5

Cat.No. Product Name Price
SHH377048 shRNA set against Human PLAU (NM_002658.3) Inquiry
SHH377052 shRNA set against Mouse PLAU (NM_008873.3) Inquiry
SHR120120 shRNA set against Rat Plau(NM_013085.3) Inquiry
SHW005936 shRNA set against Chicken PLAU (NM_205443) Inquiry
Cat.No. Product Name Price
CDCS408443 Human PLAU ORF Clone (BC013575) Inquiry
CDFH014445 Human PLAU cDNA Clone(NM_001145031.1) Inquiry
CDFR010887 Rat Plau cDNA Clone(NM_013085.3) Inquiry
MiUTR1R-05889 PLAU miRNA 3'UTR clone Inquiry
MiUTR3H-02385 PLAU miRNA 3'UTR clone Inquiry
MiUTR3H-02386 PLAU miRNA 3'UTR clone Inquiry
CDCB167411 Chicken PLAU ORF Clone (NM_205443) Inquiry
CDCB180310 Rabbit PLAU ORF clone (XM_008269903.1) Inquiry
CDCH064588 human PLAU ORF clone (NM_001145031.1) Inquiry
CDCL185743 Human PLAU ORF clone(NM_002658.3) Inquiry
CDCR246249 Mouse Plau ORF Clone(NM_008873.3) Inquiry
CDCR377964 Rat Plau ORF Clone(NM_013085.3) Inquiry
Cat.No. Product Name Price
CC-1089 PLAU Easy KO Kit Inquiry
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