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PGAP3


Official Full Name
post-GPI attachment to proteins phospholipase 3
Organism
Homo sapiens
Gene ID
93210
Background
This gene encodes a glycosylphosphatidylinositol (GPI)-specific phospholipase that primarily localizes to the Golgi apparatus. This ubiquitously expressed gene is predicted to encode a seven-transmembrane protein that removes unsaturated fatty acids from the sn-2 position of GPI. The remodeling of the constituent fatty acids on GPI is thought to be important for the proper association between GPI-anchored proteins and lipid rafts. The tethering of proteins to plasma membranes via posttranslational GPI-anchoring is thought to play a role in protein sorting and trafficking. Mutations in this gene cause an autosomal recessive form of neurologic hyperphosphatasia with cognitive disability (HPMRS4). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
Synonyms
CAB2; PERLD1; PP1498; hCOS16; AGLA546

Cat.No. Product Name Price
CDFG006849 Human PGAP3 cDNA Clone(NM_033419.3) Inquiry
CDFG017896 Mouse Pgap3 cDNA Clone(NM_001033537.2) Inquiry
MiUTR1H-07787 PGAP3 miRNA 3'UTR clone Inquiry
MiUTR1M-09109 PGAP3 miRNA 3'UTR clone Inquiry
CDCB173815 Danio rerio PGAP3 ORF Clone (NM_001114591) Inquiry
CDCB184693 Rabbit PGAP3 ORF clone (XM_008271414.1) Inquiry
CDCL148383 Human Pgap3 ORF clone (NM_001033537.2) Inquiry
CDCR313906 Human PGAP3 ORF Clone(NM_033419.3) Inquiry
CDCS416513 Human PGAP3 ORF Clone (BC010652) Inquiry
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