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PEX19


Official Full Name
peroxisomal biogenesis factor 19
Organism
Homo sapiens
Gene ID
5824
Background
This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Synonyms
PXF; HK33; PMP1; PMPI; PXMP1; PBD12A; D1S2223E

Cat.No. Product Name Price
SHH373732 shRNA set against Human PEX19 (NM_002857.3) Inquiry
SHH373736 shRNA set against Mouse PEX19 (NM_023041.3) Inquiry
SHH373740 shRNA set against Rat PEX19 (NM_001134777.1) Inquiry
SHW008204 shRNA set against Danio rerio PEX19 (NM_001017399) Inquiry
Cat.No. Product Name Price
CDCS409295 Human PEX19 ORF Clone (BC000496) Inquiry
CDFR007074 Rat Pex19 cDNA Clone(NM_001107375.2) Inquiry
CDFR010002 Rat Pex19 cDNA Clone(NM_001134777.1) Inquiry
MiUTR4H-TG06614 PEX19 miRNA 3'UTR clone Inquiry
CDCB158785 Human PEX19 ORF clone (BC000496) Inquiry
CDCB169679 Danio rerio PEX19 ORF Clone (NM_001017399) Inquiry
CDCL148161 Human PEX19 ORF clone (NM_001193644.1) Inquiry
CDCL148165 Mouse Pex19 ORF clone (NM_001159525.1) Inquiry
CDCR374086 Rat Pex19 ORF Clone(NM_001107375.2) Inquiry
CDCR377013 Rat Pex19 ORF Clone(NM_001134777.1) Inquiry
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