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P2RXL1

Official Full Name
purinergic receptor P2X 6
Organism
Homo sapiens
GeneID
9127
Background
The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]
Synonyms
P2RX6; P2X6; P2XM; P2RXL1;

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