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NFU1

Official Full Name
NFU1 iron-sulfur cluster scaffold
Organism
Homo sapiens
GeneID
27247
Background
This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Synonyms
Nfu; NifU; HIRIP; MMDFS; MMDS1; NIFUC; SPG93; CGI-33; HIRIP5;

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