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NCR3


Official Full Name
natural cytotoxicity triggering receptor 3
Organism
Homo sapiens
Gene ID
259197
Background
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
Synonyms
1C7; MALS; CD337; LY117; NKp30

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