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NSMCE2


Official Full Name
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
Organism
Homo sapiens
Gene ID
286053
Background
This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017]
Synonyms
NSE2; MMS21; ZMIZ7; C8orf36

Cat.No. Product Name Price
SHH355404 shRNA set against Human NSMCE2 (NM_173685.2) Inquiry
SHH355408 shRNA set against Mouse NSMCE2 (NM_026746.3) Inquiry
SHH355412 shRNA set against Rat NSMCE2 (NM_001024876.1) Inquiry
SHW003804 shRNA set against Chicken NSMCE2 (NM_001277463) Inquiry
Cat.No. Product Name Price
CDFG020680 Mouse Nsmce2 cDNA Clone(NM_001164604.1) Inquiry
CDFR003712 Rat Nsmce2 cDNA Clone(NM_001024876.1) Inquiry
MiUTR1R-06441 NSMCE2 miRNA 3'UTR clone Inquiry
MiUTR4H-TG06143 NSMCE2 miRNA 3'UTR clone Inquiry
CDCB165279 Chicken NSMCE2 ORF Clone (NM_001277463) Inquiry
CDCB184005 Rabbit NSMCE2 ORF clone (XM_008255900.1) Inquiry
CDCL140108 Human NSMCE2 ORF clone (NM_173685.2) Inquiry
CDCL140113 Mouse Nsmce2 ORF clone (NM_001164604.1) Inquiry
CDCR259176 Mouse Nsmce2 ORF Clone(NM_026746.3) Inquiry
CDCR370473 Rat Nsmce2 ORF Clone(NM_001024876.1) Inquiry
CDCS417451 Human NSMCE2 ORF Clone (BC032797) Inquiry
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