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NEFL


Official Full Name
neurofilament light chain
Organism
Homo sapiens
Gene ID
4747
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
Synonyms
NFL; NF-L; NF68; CMT1F; CMT2E; CMTDIG; PPP1R110

Cat.No. Product Name Price
SHH351124 shRNA set against Human NEFL (NM_006158.3) Inquiry
SHH351128 shRNA set against Mouse NEFL (NM_010910.1) Inquiry
SHH351132 shRNA set against Rat NEFL (NM_031783.1) Inquiry
Cat.No. Product Name Price
CDCL185448 Human NEFL ORF clone(NM_006158.3) Inquiry
CDCS412581 Human NEFL ORF Clone (BC066952) Inquiry
CDFR012915 Rat Nefl cDNA Clone(NM_031783.1) Inquiry
MiUTR1M-07585 NEFL miRNA 3'UTR clone Inquiry
MiUTR1R-04162 NEFL miRNA 3'UTR clone Inquiry
MiUTR3H-01528 NEFL miRNA 3'UTR clone Inquiry
CDCB186054 Rabbit NEFL ORF clone (XM_008249462.1) Inquiry
CDCL137493 Human Nefl ORF clone (NM_010910.1) Inquiry
CDCR379929 Rat Nefl ORF Clone(NM_031783.1) Inquiry
CDCS412582 Human NEFL ORF Clone (BC039237) Inquiry
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